pentobarbital will minimize the extent or effect of ritonavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

pentobarbital will lessen the extent or impact of cilostazol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.

pentobarbital will minimize the level or result of lumacaftor/ivacaftor by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.

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Sufferers stabilized on corticosteroid therapy might need dosage adjustments if barbiturates are additional to or withdrawn from their dosage routine as a result of induction of hepatic microsomal enzymes by barbiturates

Work out warning when administered to sufferers with acute or chronic discomfort; could bring about paradoxical pleasure or essential indications could possibly be masked

pentobarbital will minimize the level or impact of theophylline by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

Observe Intently (one)pentobarbital will reduce the level or outcome of mestranol by impacting website hepatic/intestinal enzyme CYP3A4 metabolism.

Check Carefully (one)pentobarbital will minimize the level or impact of levamlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

Monitor Closely (1)pentobarbital will reduce the level or impact of cannabidiol by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will lower the extent or result of pioglitazone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unfamiliar.

pentobarbital will decrease the extent or result of temsirolimus by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.

Contraindicated (1)pentobarbital will lower the level or impact of lorlatinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

Watch Closely (1)pentobarbital will minimize the level or influence of fentanyl transmucosal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Coadministration of fentanyl with CYP3A4 inducers could lead into a lessen in fentanyl plasma concentrations, lack of efficacy or, perhaps, enhancement of a withdrawal syndrome within a client who's got designed physical dependence to fentanyl. Soon after stopping a CYP3A4 inducer, given that the effects with the inducer drop, the fentanyl plasma concentration will increase which could boost or lengthen both the therapeutic and adverse effects.